Weekends From Miami: The Keys, the Everglades and Inland
Weekend TripsRoad Trip🌎 Islamorada

Weekends From Miami: The Keys, the Everglades and Inland

Miami's weekends run down a single highway into the Keys or west into swamp, and the two could not be more different.

Weekend Trip Editorial

August 21, 2026 · 3 min read

Key takeaways

  • Miami's weekends go in essentially two directions: south down a single highway into the Keys, or west into the Everglades.
  • One road, US-1, with mile markers counting down to zero at Key West.
  • An hour west, and a completely different landscape — a slow, shallow river of grass rather than a swamp.
  • A short flight to Nassau or the Exumas is a genuine weekend option from Miami and is worth pricing against a long drive.

Miami's weekends go in essentially two directions: south down a single highway into the Keys, or west into the Everglades. They are about as different as two places 60 miles apart can be.

The Keys, by mile marker in Islamorada

The Keys, by mile marker

One road, US-1, with mile markers counting down to zero at Key West.

Key Largo (MM 100), an hour — John Pennekamp State Park, protecting the only living coral barrier reef in the continental United States. Snorkelling and diving trips run daily.

Islamorada (MM 80) — sport fishing, and the best restaurants in the upper Keys.

Marathon (MM 50) — the turtle hospital, and the start of the Seven Mile Bridge.

Bahia Honda (MM 37) — the best beach in the Keys.

Key West (MM 0), three and a half to four hours — Duval Street, Hemingway's house with its six-toed cats, Mallory Square at sunset, and the southernmost point.

The upper and middle Keys often make better two-night trips than Key West, because the drive is half as long and the prices are lower.

The Everglades

An hour west, and a completely different landscape — a slow, shallow river of grass rather than a swamp.

The Anhinga Trail at Royal Palm — a short boardwalk where alligators, anhingas and herons are visible at close range. The best wildlife per minute in Florida, and it is free with park entry.

Shark Valley — a 15-mile loop by tram or bicycle, with alligators lying beside the path.

Ten Thousand Islands, on the Gulf side, for paddling among mangroves.

Airboats are loud and cover ground fast. The quieter options show more, because animals do not move away from a silent approach.

The Gulf coast in Islamorada

The Gulf coast

Naples, two hours across Alligator Alley — beaches, a pier, and calm Gulf water.

Sanibel and Captiva, three hours — shelling beaches, and a wildlife refuge.

Marco Island, and the Ten Thousand Islands beyond it.

North

DestinationDrive
Palm Beach1h15
Vero Beach2h30
Sarasota3h30
Orlando3h30
BahamasShort flight

A short flight to Nassau or the Exumas is a genuine weekend option from Miami and is worth pricing against a long drive.

Seasons in Islamorada

Seasons

December to April is the dry season — lower humidity, fewer mosquitoes, and better wildlife viewing as animals concentrate around the water that remains.

Summer is hot, humid and wet, with afternoon storms.

Hurricane season runs June to November, with peak risk in late summer. Check forecasts and consider flexible bookings in that window.

Practical

US-1 has limited overtaking. One incident backs up the whole highway, and there is no alternative route.

Leave Friday before noon or after 8pm, and return Sunday morning or late.

Book Keys accommodation well ahead in the dry season, particularly Key West.

Mosquito repellent for the Everglades, year round, and heavily in summer.

Frequently asked questions

How long does it take to drive to Key West from Miami?

Around three and a half to four hours without traffic, on a single highway with limited overtaking. Weekend traffic and any incident can extend it considerably, which is why the upper and middle Keys — Key Largo, Islamorada and Marathon — often make better two-night destinations.

Are Everglades airboat tours worth it?

They are loud and they cover ground quickly, which suits some visitors. The quieter alternatives — the Anhinga Trail boardwalk, Shark Valley's tram and bike path, and paddling in the Ten Thousand Islands — show more wildlife and cost less, since alligators do not move away from a silent approach.

When is the best time to visit south Florida?

December to April, the dry season, with lower humidity, fewer mosquitoes and better wildlife viewing as animals concentrate around remaining water. Summer is hot, humid and wet, and hurricane season runs June to November with peak risk in late summer.

What is there to do in the Keys besides Key West?

Snorkelling and diving at John Pennekamp in Key Largo, which protects the only living coral barrier reef in the continental US, sport fishing from Islamorada, Bahia Honda's beach, and the seven-mile bridge. The upper and middle Keys are quieter and cheaper than Key West.

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